Controlled assembly of covalent and supramolecular chemical modules: from engineering of complex structures to high-performance chromatography

Publication Type:

Journal Article

Source:

RUSSIAN CHEMICAL BULLETIN, CONSULTANTS BUREAU, Volume 53, Number 7, 233 SPRING ST, NEW YORK, NY 10013 USA, p.1379-1384 (2004)

Keywords:

AMPLIFICATION; AUTOCATALYSIS; BIPHASIC ALKALINE-HYDROLYSIS; BROWNIAN PARTICLES; C-8 ETHYL ALKANOATES; DNA; MODELS; MOLECULAR MOTORS; REVERSE MICELLES; SELF-REPLICATING SYSTEM

Abstract:

A biological approach to generating complex behaviors in chemistry is described. It is suggested theoretically that the assembly of ``modules{''} composed of chemical reactions or molecular structures under appropriate external constraints can lead to features typical of the biological world like autocatalysis, kinetic proofreading, or oriented molecular motion. This approach may account for the primitive steps of molecular evolution and, in addition, it can find useful applications in chemistry such as high -performance chromatography.