Magnetic tweezers for the study of DNA tracking motors

Publication Type:

Journal Article

Source:

Methods in enzymology, Volume 475, p.297-320 (2010)

Keywords:

DNA Helicases; Magnetics; Mitochondrial ADP, ATP Translocases; Torsion, Mechanical

Abstract:

Single-molecule manipulation methods have opened a new vista on the study of molecular motors. Here we describe the use of magnetic traps for the investigation of the mechanism of DNA based motors, in particular helicases and translocases.