Single-molecule manipulation measurements of DNA transport proteins

Publication Type:

Journal Article

Source:

CHEMPHYSCHEM, WILEY-V C H VERLAG GMBH, Volume 6, Number 5, PO BOX 10 11 61, D-69451 WEINHEIM, GERMANY, p.813-818 (2005)

DOI:

10.1002/cphc.200400635

Keywords:

BACILLUS-SUBTILIS; F-1-ATPASE; MOTOR PROTEIN; PROTON MOTIVE FORCE; RECOMBINATION; RNA-POLYMERASE; SUPERCOILED DNA; TRANSCRIPTION; TRANSFORMATION; TRANSLOCATION

Abstract:

Single-molecule measurements of the manipulation of three different DNA motor proteins are reviewed. Despite some differences in the structure and mechanisms of the proteins, there are consistent phenomenological themes that relate them. Each of the experiments described represents a significant advance in the understanding of the mechanisms of DNA transport.